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This book discusses the critical contemporary issues of sustainability and integration of physical and information flow. It explores the digitalization of logistics processes and the need for a more integrated and a seamless cooperation in supply chain management, which are dominant trends in business practice. Moreover, it examines how the pressure for CO2 emission reductions and more resource- efficient business models influences the organization of logistics operations on both a local and global scale, demonstrating that integrating physical and cyber systems is necessary to achieve a more environmentally friendly, safe logistics and supply chain operations. In the individual chapters, the authors discuss the new qualitative and quantitative theoretical methods and models and also analyze case studies from business practice. This book provides valuable insights for academics, Ph.D. students and practitioners wishing to deepen their understanding of logistics operations and management.